2-Methacryloyloxyethyl phosphorylcholine (MPC) amphoteric zwitterionic methacrylate monomer containing a phosphocholine group outstanding protein adsorption excellent biocompatibility low toxicity

2-Methacryloyloxyethyl phosphorylcholine (MPC) amphoteric zwitterionic methacrylate monomer containing a phosphocholine group outstanding protein adsorption excellent biocompatibility low toxicity

Specification of 2-Methacryloyloxyethyl phosphorylcholine (MPC) amphoteric zwitterionic methacrylate monomer containing a phosphocholine group outstanding protein adsorption excellent biocompatibility low toxicity

Description of 2-Methacryloyloxyethyl phosphorylcholine (MPC) amphoteric zwitterionic methacrylate monomer containing a phosphocholine group outstanding protein adsorption excellent biocompatibility low toxicity

2-Methacryloyloxyethyl phosphorylcholine (MPC) is a zwitterionic compound designed and synthesized based on the structure of the outer cell membrane. It exhibits excellent biocompatibility and strong hydrophilicity. Materials modified with MPC demonstrate improved thermal and chemical stability, superior blood and tissue compatibility, and effectively enhance surface lubrication while reducing interfacial friction. For example:

Modifying polymers such as methyl methacrylate (MMA) or butyl methacrylate (BMA) with MPC significantly enhances their blood compatibility.

Copolymers of MPC, BMA, and methacryloyl hydrazide (MH) are increasingly used in controlled drug release applications.

MPC copolymers contain a high amount of free water on their surface, forming a tightly bound hydration layer that effectively inhibits protein adsorption, making them an ideal material for contact lenses.

Beyond these applications, MPC copolymers are also widely used in various fields, including protein separation, cosmetic additives, hemodialysis membranes, gene carriers, joint wear resistance improvement, and biosensors.

Advantages of 2-Methacryloyloxyethyl phosphorylcholine (MPC) amphoteric zwitterionic methacrylate monomer containing a phosphocholine group outstanding protein adsorption excellent biocompatibility low toxicity

2-Methacryloyloxyethyl phosphorylcholine (MPC) is an amphoteric zwitterionic methacrylate monomer containing a phosphocholine group. This compound exhibits outstanding properties such as resistance to nonspecific protein adsorption, excellent biocompatibility, and low toxicity, making it widely used in the preparation of various polymeric biomaterials.

Due to the presence of a zwitterionic phosphorylcholine (PC) group on its side chain, MPC demonstrates unique biological inertness and can efficiently construct diverse molecular structures with tunable properties. It exhibits remarkable resistance to cell adhesion, anticoagulation, and nonspecific protein adsorption. As a zwitterionic methacrylate monomer containing a phosphocholine group, MPC is the most suitable monomer for mimicking the polar groups of cell membrane phospholipids.

MPC can be utilized to develop various molecular architectures with adjustable properties through a range of polymerization methods, including living radical polymerization. Owing to the reactivity of the methacrylate group, polymeric materials based on MPC have broad applications in the biomedical field. Additionally, MPC serves as a monomer for producing various polymeric materials used in medical devices, lithium-based batteries, contact lenses, drug delivery systems, wound dressings, and tissue engineering scaffolds.

Applications of 2-Methacryloyloxyethyl Phosphorylcholine (MPC):

It can be used as a monomer to produce fully zwitterionic polymers in ionic liquid solvents, serving as gel electrolytes for lithium-based batteries.

MPC is employed in the synthesis of polymer coatings for medical devices to prevent blood clotting and bacterial adhesion.

Furthermore, this compound is used in the preparation of hydrogels for contact lens materials and wound dressings.

FAQ

Q1: What is your regular lead time for sample and official order?

A1: Sample lead time 5-7 days. Official order lead time 14-21 days.

Q2: What is your MOQ?

A2: MOQ usually is 1kg.

Q3: How you control product quality?

A3: From raw material inspection, dupro inspection to final product inspection are executed strictly.

Q4: What is your warranty policy?

A4: We will send you a new batch if there is any quality issue during warranty time

Q5: Do you refund if customer receive defective product and do not accept replacement?

A5: Yes

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